Over the years, borderline personality disorder (BPD) has been conceptualized in a variety of ways. However, recent research has consistently found that a history of childhood sexual abuse may affect its development. Role of Sexual Abuse in the Etiology of Borderline Personality Disorder explores the most recent advances regarding this highly controversial disorder, presenting the research and expertise of 26 distinguished contributors. This book provides both the factual and the historical contexts of sexual abuse in BPD. It presents the latest findings regarding the impact of traumatic childhood experiences on the development of BPD. This new generation of research is unique in that it assesses a range of pathological childhood experiences rather than focusing solely on the parameters of abuse. This book covers many topics, including evolving perspectives on the etiology of BPD, childhood factors associated with the development of BPD, and the relationship between self-destructive behavior and pathological childhood experiences in BPD. In addition, highly regarded clinicians in this area describe useful clinical approaches to the treatment of borderline patients with an abuse history. This volume offers invaluable information for clinicians treating borderline patients with or without an abuse history.
This volume presents a timely account of the present state of ECT research and clinical practice and the irreplaceable niche ECT occupies in the treatment hierarchy of severe mental illness. Interdisciplinary contributors to The Clinical Science of Electroconvulsive Therapy use both longitudinal and cross-sectional perspectives to synthesize the latest information on ECT. This book reviews -- comprehensively and carefully -- today's knowledge of indications, techniques, clinical outcomes, and mechanisms of action of ECT.
Until several decades ago, few studies were conducted on the differences among individual responses to pharmacologic agents. Then, in the 1950s and 1960s, enzyme induction was discovered, and it became apparent that the intake of certain foods or drugs could adaptively modify drug metabolism and, therefore, drug response. Now researchers are beginning to realize how both adaptive and genetic forces may cause pharmacological distinctions among human populations once separated by distance or geographical boundaries. Psychopharmacology and Psychobiology of Ethnicity provides a unique overview of how ethnically defined populations respond to psychoactive drugs. Its renowned contributors review and summarize our current knowledge of ethnic differences and similarities among patients in response to psychotropic drugs.
One of the major challenges for mental health professionals today is to successfully treat violent patients. The mental health professional is obligated to go beyond containment and control to provide understanding, complete assessment and accurate diagnosis, and humane and effective treatment. Understanding and Treating Violent Psychiatric Patients is a one-of-a-kind, comprehensive guide to assessment, management, understanding, and treatment of violent patients. The first section encompasses practical guides to treatment for both children and adults. It discusses commonly encountered problems in the treatment of violent adult inpatients and includes a brief guide to pharmacological treatments. A chapter is devoted to the treatment of abnormal aggression in children and adolescents. The second section delves into a more conceptual and broadly focused approach to understanding violent patients. It covers the relationship between dissociation and violence, as well as the relationship between psychiatric disorders and violence, and addresses impulse control and the treatment of impulsive patients. Heavily researched and clinically focused, this new title is a "must read" for psychiatrists, psychologists, psychiatric social workers, psychiatric nurses, or any mental health professional needing a better approach to understanding and treating violent patients.
Written and edited by some of the world's foremost experts in the field, Trauma, Memory, and Dissociation provides comprehensive coverage of dissociation and memory alterations in trauma, an area that is being dramatically reshaped by vigorous new research. This one-of-a-kind book, written for researchers and clinicians alike, covers aspects of this subject that have not been thoroughly examined before. It presents empirical data on dissociative symptoms associated with exposure to psychological trauma, including combat, childhood abuse, and other traumas, as well as the important relationships dissociative disorder has with other conditions associated with extreme stress such as posttraumatic stress disorder. This book also examines areas where questions still linger concerning the psychopathology of trauma-related dissociation, including dissociation as a defense mechanism or a normal personality trait. Because dissociation plays an important role in the recall of traumatic memories, Trauma, Memory, and Dissociation investigates the controversial areas of delayed recall of childhood abuse and "false memory syndrome." This text also offers clinicians a detailed, step-by-step discussion of approaches to treat the dissociative patient. It reviews the neurobiology of dissociative disorders and illuminates areas where future research may lead to more effective treatments.
Psychoneuroimmunology has emerged as a discipline advancing our knowledge of the relationships among psychosocial factors, the central nervous system, the immune system, and disease. The growing volume of evidence suggests that psychological states, including exposure to stressors and the presence of depressive states, may influence health and disease by altering immunologic states. Psychoneuroimmunology, a collaborative work of 50 international experts, expands on the American Psychiatric Association's symposium on this topic to present never-before-compiled scientific research from this evolving field. Maintaining a clinical focus, this book illustrates clinical effects by examining relevant research studies and models including Psychoneuroimmunological factors involved in specific illnesses such as cervical cancer, breast cancer and HIV/AIDS The role psychoneuroimmunology plays in carcinogenesis and the progression of established tumors, as well as findings on the progression of cancer that have general clinical relevance The effects of specific psychotropic medications; the effects of life stressors, bereavement, and and social support; the response to those stressors; and stress management and psychosocial predictors of disease The impacts of gender-specific factors, diurnal variation, and behavioral genetics on the immune function The Stressor-Support-Coping model, which integrates existing psychoneuroimmunology findings and lays the groundwork for use in support group intervention This book is a first step toward organizing psychoneuroimmunology findings into coherent theoretical models and concludes with a look at future clinical applications. Complete with charts, references, and a detailed index, it is the most comprehensive source on psychoneuroimmunology.
Melatonin in Psychiatric and Neoplastic Disorders provides psychiatrists, oncologists, endocrinologists, pediatricians, and other health professionals with a thorough examination of the most current research on the role of melatonin in psychiatric and neoplastic disorders.
The 1990s, appropriately termed "the decade of the brain," witnessed unprecedented advances in our knowledge of psychiatric neuroscience. Yet with every advance, we realized afresh that we were still in the beginning stages of a much longer journey. This text chronicles the next step of that journey. Structured around a proven teaching methodology that uniquely integrates the clinical aspects of psychiatric disorders with their neurobiology, this volume begins with two introductory chapters on functional neural circuitry and neural signaling pathways. The remaining six chapters present current knowledge on the neuroanatomic and neurochemical mechanisms underlying schizophrenia, addiction, anxiety, depression, bipolar disorder, and dementia/Alzheimer's disease. For clarity and consistency, each chapter features the same four divisions -- clinical presentation, neural circuitry, signaling pathways, and psychopharmacology -- as they relate to Schizophrenia, which reviews studies of the neural basis of schizophrenia and describes how the cortex, the thalamus, the basal ganglia, and the medial temporal lobe work together during normal brain function and then how each is perturbed in psychosis. Addiction, which focuses on the consequences of psychoactive substance use, including compulsive practices (e.g., eating, sex, Internet browsing) that might also involve the same brain circuits and signaling pathways. Of exceptional value are two unique illustrations that capture -- for the first time -- much of what we know about the anatomy and neurochemistry underlying the behavioral symptoms of addiction. Anxiety, which presents current hypotheses regarding neurocircuitry and signaling pathways for the three best-studied (from a neurobiologic perspective) anxiety disorders: panic disorder, posttraumatic stress disorder, and obsessive-compulsive disorder. Depression, which offers evidence for the involvement of highly interconnected cortical and limbic structures such as the prefrontal cortex, medial thalamus, amygdala, ventral striatum, hippocampus, and the hypothalamic-pituitary-adrenal axis in unipolar major depression, and suggests target areas (such as the cAMP pathway) for study in the development of new antidepressants. Bipolar disorder, which shows that specific abnormalities in signal transduction pathways, including protein kinase activity, G protein levels, and gene expression, are unique to bipolar patients, concluding that the actions of lithium and anticonvulsants on intracellular signaling pathways provide a new paradigm for novel pharmacological interventions. Dementia and Alzheimer's disease, which details current findings on neurofibrillary degeneration, relevant genes and proteins, pathogenesis (metabolic decline, defective cell repair, and Aß toxicity), and treatment strategies (neurotransmitter replacement, and neuroprotective and regenerative approaches). Discusses frontotemporal dementia, dementia with Lewy bodies, Parkinson's disease, and vascular dementia. Meticulously researched and clearly written by 15 contributors -- all recognized experts from leading research and teaching institutions in the United States -- this compact and extensively illustrated volume stands out in the literature because it combines readability and practicality with the breadth and depth typically found only in far lengthier works. Psychiatric practitioners, residents, and students alike will welcome this informative, easy-to-read text, which will also be of special interest to mental health and pharmaceutical industry professionals, and of general interest to anyone who wants to know more about the biology of psychiatric illness.
Biological Rhythms, Mood Disorders, Light Therapy, and the Pineal Gland combines the experience of psychiatric clinicians, psychiatric residents, medical students, endocrinologists, psychoimmunologists, neurobiologists, neuroanatomists, and other health professionals to present the most recent progress made in the study of the pineal gland and its relationship to mood disorders, including * major depressive disorders* winter depression* bipolar disorders* premenstrual syndrome (PMS)* sleep disorders The use of bright light to treat these disorders is also discussed.