Biology of Disease

Author: Nessar Ahmed,Maureen Dawson,Chris Smith,Ed Wood

Publisher: Garland Science

ISBN: 1135728712

Category: Science

Page: 600

View: 950

Biology of Disease describes the biology of many of the human disorders and disease that are encountered in a clinical setting. It is designed for first and second year students in biomedical science programs and will also be a highly effective reference for health science professionals as well as being valuable to students beginning medical school. Real cases are used to illustrate the importance of biology in understanding the causes of diseases, as well as in diagnosis and therapy.

The Biology of Disease

Author: Jonathan Phillips,Paul G. Murray,Paul Kirk

Publisher: Wiley-Blackwell

ISBN: 9780632054046

Category: Medical

Page: 340

View: 4331

The second edition of The Biology of Disease is an introductory level text on the biological principles of human disease. The book is aimed at medical students in degree courses in biomedical science. The book fuses the biological (physiological and biochemical) processes which underlie the clinical manifestations of disease. As such, it brings together material which is conventionally dealt with by several books. The authors have covered the fundamentals of each topic in a readable manner, which should encourage students to develop a fuller understanding, where necessary, by reference to more comprehensive texts. Integrates basic science and clinical medicine. Detailed case studies at the end of each chapter which emphasise the clinical setting. New chapters on transplantation immunology, anaemia, toxicology & poisoning. The use of non-technical language for the descriptions in the case studies to ensure that all students will comprehend the underlying principles.

Biology of Disease Vectors

Author: William H. Marquardt

Publisher: Elsevier

ISBN: 0080494064

Category: Science

Page: 816

View: 303

Biology of Disease Vectors presents a comprehensive and advanced discussion of disease vectors and what the future may hold for their control. This edition examines the control of disease vectors through topics such as general biological requirements of vectors, epidemiology, physiology and molecular biology, genetics, principles of control and insecticide resistance. Methods of maintaining vectors in the laboratory are also described in detail. No other single volume includes both basic information on vectors, as well as chapters on cutting-edge topics, authored by the leading experts in the field. The first edition of Biology of Disease Vectors was a landmark text, and this edition promises to have even more impact as a reference for current thought and techniques in vector biology. Current - each chapter represents the present state of knowledge in the subject area Authoritative - authors include leading researchers in the field Complete - provides both independent investigator and the student with a single reference volume which adopts an explicitly evolutionary viewpoint throuoghout all chapters. Useful - conceptual frameworks for all subject areas include crucial information needed for application to difficult problems of controlling vector-borne diseases

The Biology of Desire

Why Addiction Is Not a Disease

Author: Marc Lewis

Publisher: PublicAffairs

ISBN: 1610394380

Category: Psychology

Page: 256

View: 4118

The psychiatric establishment in the Western world has unanimously branded addiction a brain disease. And the idea that an addict has an incurable illness, as opposed to a contemptible moral weakness, has served an historically important role in changing how addiction is understood, researched, and treated throughout the world. But as renowned developmental neuroscientist and recovered addict Marc Lewis argues in this illuminating, compelling, likely controversial book, addiction is not in fact a disease. Addiction, whether to drugs, alcohol, gambling, food, sex, or cigarettes, is rather a developmental learning process resulting from the normal functioning of the human brain. Through vividly rendered, compassionate stories of five addicts, interpreted in the light of state-of-the-art neuroscientific knowledge, Lewis shows how the compulsion to use arises in a brain that is highly efficient in pursuing singular goals. He reveals addiction as an unfortunate twist of fate for a brain doing what it’s designed to do—seek pleasure and relief—in a world that’s not cooperating. He shows that recovery from addiction is indeed possible,and that it is nothing like remission from a disease, because brain physiology doesn't need to change for addicts to get better. The Biology of Desire is vital and enlightening reading for anyone who has wrestled with addiction themselves, in their families, or as a medical or treatment professional. It illuminates a path to more effective treatment for addicts, and limns the essential requirements for individual recovery. Combining clearly rendered scientific explanation with insight, compassion, and even humor, Lewis boldly challenges us all to re-examine our approach to addiction, and whether the metaphors we've used to explain it have now become obstacles to healing.


Fundamental Biology and Mechanisms of Disease

Author: Joseph Hill

Publisher: Academic Press

ISBN: 012381510X


Page: 1398

View: 8875


Biology of Disease

Author: Roz Gibbs,Sheelagh Heugh

Publisher: OUP Oxford

ISBN: 9780199539574

Category: Medical

Page: 368

View: 9524

Biology of Disease addresses the pathophysiology of specific disease states and evaluates the multidisciplinary approach to disease diagnosis and management. Starting with an introduction to the basic concepts of health and disease, the book graduates to an in-depth discussion of disease states, while illustrating how theory is linked to practice.

Genetics of Bone Biology and Skeletal Disease

Author: Rajesh V. Thakker,Michael P. Whyte,John Eisman,Takashi Igarashi

Publisher: Academic Press

ISBN: 0128041986

Category: Medical

Page: 878

View: 2720

Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder


Structure, Biology and Disease

Author: Stephen M. King,King M. Stephen

Publisher: Academic Press

ISBN: 0123820049

Category: Medical

Page: 639

View: 1224

With an accompanying Web site showing more than 100 streaming videos of cell dynamic behavior for best comprehension of material, "Dyneins" is the only reference covering the structure, biology, and application of dynein research to human disease. From bench to bedside, this book offers research on fundamental cellular processes to researchers and clinicians across developmental biology, cell biology, molecular biology, biophysics, biomedicine, genetics, and medicine.

Molecules, Cells, and Disease

An Introduction to the Biology of Disease

Author: J.L. VanLancker

Publisher: Springer Science & Business Media

ISBN: 146139418X

Category: Medical

Page: 311

View: 6101

In tracing their origin and their fate, the beginning and the end of their environment, humans have often been guided by curiosity. Such concern has helped man to discover, among other things, the structure of the universe from star to atom and the evolution of life from unicellular organism to human being. The study of disease is unique. Although it may have been in spired by the curiosity of a few, it has always been the concern of all, because preventing or curing disease has meant survival not only of individuals, but of entire nations, not only of humans, but of fellow living creatures. If greed, force, religion, and language have been major causes of wars, diseases, more than arms, have often decided the outcome of battles and thereby have woven the pattern of history. For millennia, a large fraction of the human race believed that disease expressed the wrath of God(s) against individuals or societies. Therefore, only priests or priestesses, kings, and queens were endowed with the power of healing. In the West, Hippocrates is credited for exorcising this concept of disease and for objectively describing and cataloguing them. The contributions of Greek physicians to Western medicine made possible more accurate diagnoses and prognoses.

Perspectives in Human Malnutrition

A Contribution to the Biology of Disease from a Clinical and Pathological Study of Chronic Malnutrition and Pellagra in the African

Author: Joseph Gillman,Theodor Gillman

Publisher: N.A


Category: Malnutrition

Page: 584

View: 2275


Molecular Biology of Placental Development and Disease

Author: N.A

Publisher: Academic Press

ISBN: 0128096020

Category: Science

Page: 274

View: 1440

Molecular Biology of Placental Development and Disease, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on placental development and disease. Contains contributions from leading authorities on the topic of placental development and disease Publishes cutting-edge reviews in molecular biology

Biology of Disease

Author: Eli Moschcowitz

Publisher: N.A


Category: Medicine

Page: 221

View: 3219


Advances in the Biology of Disease

Author: Emanuel Rubin,Ivan Damjanov

Publisher: N.A


Category: Diseases

Page: N.A

View: 820


Systems Biology of Parkinson's Disease

Author: Peter Wellstead,Mathieu Cloutier

Publisher: Springer Science & Business Media

ISBN: 1461434114

Category: Science

Page: 176

View: 6493

The Systems Biology of Parkinson’s Disease will be underpinned by new measurement techniques. This is particularly true of the pathology of Parkinson's Disease, where recent developments in brain imaging have offered new insights into the morphology of dopaminergic neurons that have profound implications for the special vulnerability and role of this class of neurons.
Technology & Engineering

Mechanobiology in Health and Disease

Author: Stefaan Verbruggen

Publisher: Academic Press

ISBN: 0128129530

Category: Technology & Engineering

Page: 527

View: 3730

Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science

Biology of C Reactive Protein in Health and Disease

Author: Waliza Ansar,Shyamasree Ghosh

Publisher: Springer

ISBN: 8132226801

Category: Medical

Page: 301

View: 7054

This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP’s significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail. The book also includes clinical data studies and presents the latest research advances to further readers’ understanding of CRP.

Biology of Bile Acids in Health and Disease

Author: G.P. van Berge Henegouwen,D. Keppler,U. Leuschner,G. Paumgartner,A. Stiehl

Publisher: Springer Science & Business Media

ISBN: 9780792387688

Category: Medical

Page: 336

View: 4923

Beginning in 1970, the International Bile Acid Meeting has taken place every two years and each time new progress in our understanding of the complex role of bile acids in many metabolic processes of the liver and the intestine has been revealed by a selected group of leading scientists from all over the world. Although originally mainly physiological data on bile acid synthesis and transport were emphasized, and later on also the therapeutic benefit of bile acids in gallstone disease and cholestasis was discovered, we have come now to the molecular biology and genetic era with major discoveries in transport defects and related diseases. This book is the proceedings of Falk Symposium No. 120, held in The Hague, The Netherlands, on October 12-13, 2000 - the 16th International Bile Acid Meeting. One of the main discoveries recently has been the identification of nuclear receptors for bile acids, which gives them a much broader perspective than previously anticipated. It even suggests that bile acids can regulate their biosynthesis and enterohepatic circulation transcriptionally. It will therefore not be surprising that this topic, together with the molecular regulation of cholesterol 7alpha-hydroxylase and cholesterol homeostasis, has a dominant place in these proceedings. Another important topic is the progress in our molecular understanding of hepatic (both at the basolateral and canalicular sites), cholangiocytic and intestinal bile acid transport processes. Further insights into genetic defects causing cholestasis or intestinal malabsorption in animal models and in human diseases are also discussed by a number of well-known authors. Finally the last section deals with new findings on the role of bile acid therapy in cholestatic syndromes or chemoprevention and with the potential benefit of bile acid inhibitors. All contributors provide an update on the most recent developments in their field.

Molecular Pathology

The Molecular Basis of Human Disease

Author: William B. Coleman,Gregory J. Tsongalis

Publisher: Academic Press

ISBN: 0128027878

Category: Medical

Page: 802

View: 9495

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase
Health & Fitness

Seaweed in Health and Disease Prevention

Author: Joël Fleurence,Ira Levine

Publisher: Academic Press

ISBN: 0128027932

Category: Health & Fitness

Page: 476

View: 978

Seaweed in Health and Disease Prevention presents the potential usage of seaweed, macroalgae, and their extracts for enhancing health and disease. The book explores the possibilities in a comprehensive way, including outlining how seaweed can be used as a source of macronutrients and micronutrients, as well as nutraceuticals. The commercial value of seaweed for human consumption is increasing year-over-year, and some countries harvest several million tons annually. This text lays out the properties and effects of seaweeds and their use in the food industry, offering a holistic view of the ability of seaweed to impact or effect angiogenesis, tumors, diabetes and glucose control, oxidative stress, fungal infections, inflammation and infection, the gut, and the liver. Combines foundational information and nutritional context, offering a holistic approach to the relationship between sea vegetables, diet, nutrition, and health Provides comprehensive coverage of health benefits, including sea vegetables as sources of nutraceuticals and their specific applications in disease prevention, such as angiogenesis, diabetes, fungal infections, and others Includes Dictionary of Terms, Key Facts, and Summary points in each chapter to enhance comprehension Includes information on toxic varieties and safe consumption guidelines to supplement basic coverage of health benefits

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

Author: Venkataramana K Sidhaye,Michael Koval

Publisher: Academic Press

ISBN: 0128038810

Category: Medical

Page: 276

View: 9661

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences