Provides students and practitioners with a clear, concise introduction to the statistics they will come across in their regular reading of clinical papers. Written by three experts with wide teaching and consulting experience, Medical Statistics: A Textbook for the Health Sciences, Fourth Edition: Assumes no prior knowledge of statistics Covers all essential statistical methods Completely revised, updated and expanded Includes numerous examples and exercises on the interpretation of the statistics in papers published in medical journals From the reviews of the previous edition: "The book has several excellent features: it is written by statisticians, is.... well presented, is well referenced.... and is short." THE LANCET "Many statisticians are concerned at the generally poor standard of statistics in papers published in medical journals. Perhaps this could be remedied if more research workers would spare a few hours to read through Campbell and Machin's book." BRITISH MEDICAL JOURNAL "... a simple, interesting and insightful introduction to medical statistics... highly recommended." STATISTICAL METHODS IN MEDICAL RESEARCH "Campbell and Machin found the golden mean... this book can be recommended for all students and all medical researchers." ISCB NEWSLETTER
This straightforward primer in basic statistics emphasizes its practical use in epidemiology and public health, providing understanding of essential topics such as study design, data analysis and statistical methods used in the execution of medical research. This new edition is substantially revised and includes entirely new material on statistical power and sample size. Clearly worded and assuming no prior knowledge, it gives full step-by-step guidance on performing statistical calculations. It contains numerous examples and exercises with detailed answers to help readers grasp the main points of these complex subjects with ease, providing doctors, nurses, health managers, researchers and students with a concise and practical guide
As many medical and healthcare researchers have a love-hate relationship with statistics, the second edition of this practical reference book may make all the difference. Using practical examples, mainly from the authors' own research, the book explains how to make sense of statistics, turn statistical computer output into coherent information, and help decide which pieces of information to report and how to present them. The book takes you through all the stages of the research process, from the initial research proposal, through ethical approval and data analysis, to reporting on and publishing the findings. Helpful tips and information boxes, offer clear guidance throughout, including easily followed instructions on how to: -develop a quantitative research proposal for ethical/institutional approval or research funding -write up the statistical aspects of a paper for publication -choose and perform simple and more advanced statistical analyses -describe the statistical methods and present the results of an analysis. This new edition covers a wider range of statistical programs - SAS, STATA, R, and SPSS, and shows the commands needed to obtain the analyses and how to present it, whichever program you are using. Each specific example is annotated to indicate other scenarios that can be analysed using the same methods, allowing you to easily transpose the knowledge gained from the book to your own research. The principles of good presentation are also covered in detail, from translating relevant results into suitable extracts, through to randomised controlled trials, and how to present a meta-analysis. An added ingredient is the inclusion of code and datasets for all analyses shown in the book on our website (http://medical-statistics.info). Written by three experienced biostatisticians based in the UK and US, this is a step-by-step guide that will be invaluable to researchers and postgraduate students in medicine, those working in the professions allied to medicine, and statisticians in consultancy roles.
A respected introduction to biostatistics, thoroughly updated andrevised The first edition of Biostatistics: A Methodology for the HealthSciences has served professionals and students alike as a leadingresource for learning how to apply statistical methods to thebiomedical sciences. This substantially revised Second Editionbrings the book into the twenty-first century for today’saspiring and practicing medical scientist. This versatile reference provides a wide-ranging look at basicand advanced biostatistical concepts and methods in a formatcalibrated to individual interests and levels of proficiency.Written with an eye toward the use of computer applications, thebook examines the design of medical studies, descriptivestatistics, and introductory ideas of probability theory andstatistical inference; explores more advanced statistical methods;and illustrates important current uses of biostatistics. New to this edition are discussions of Longitudinal data analysis Randomized clinical trials Bayesian statistics GEE The bootstrap method Enhanced by a companion Web site providing data sets, selectedproblems and solutions, and examples from such current topics asHIV/AIDS, this is a thoroughly current, comprehensive introductionto the field.
This book presents new and powerful advanced statistical methods that have been used in modern medicine, drug development, and epidemiology. Some of these methods were initially developed for tackling medical problems. All 29 chapters are self-contained. Each chapter represents the new development and future research topics for a medical or statistical branch. For the benefit of readers with different statistical background, each chapter follows a similar style: the explanation of medical challenges, statistical ideas and strategies, statistical methods and techniques, mathematical remarks and background and reference. All chapters are written by experts of the respective topics.
A new edition of the classic guide to the use of statistics inmedicine, featuring examples from articles in the New EnglandJournal of Medicine Medical Uses of Statistics has served as one of the mostinfluential works on the subject for physicians,physicians-in-training, and a myriad of healthcare experts who needa clear idea of the proper application of statistical techniques inclinical studies as well as the implications of theirinterpretation for clinical practice. This Third Editionmaintains the focus on the critical ideas, rather than themechanics, to give practitioners and students the resources theyneed to understand the statistical methods they encounter in modernmedical literature. Bringing together contributions from more than two dozendistinguished statisticians and medical doctors, this volumestresses the underlying concepts in areas such as randomizedtrials, survival analysis, genetics, linear regression,meta-analysis, and risk analysis. The Third Editionincludes: Numerous examples based on studies taken directly from the pagesof the New England Journal ofMedicine Two added chapters on statistics in genetics Two new chapters on the application of statistical methods tostudies in epidemiology New chapters on analyses of randomized trials, linearregression, categorical data analysis, meta-analysis, subgroupanalyses, and risk analysis Updated chapters on statistical thinking, crossover designs,p-values, survival analysis, and reporting research results A focus on helping readers to critically interpret publishedresults of clinical research Medical Uses of Statistics, Third Edition is a valuableresource for researchers and physicians working in anyhealth-related field. It is also an excellent supplemental book forcourses on medicine, biostatistics, and clinical research at theupper-undergraduate and graduate levels. You can also visit the NewEngland Journal of Medicine website for relatedinformation.
There has been a growing recognition of the importance of mathematical and statistical methods in the history of medicine, particularly in those areas where statistical methods are a sine qua non such as epidemiology and randomised clinical trials. Despite this expanding scholarly interest, the development of the mathematical and statistical technologies in the biological sciences has not been examined systematically. This collection of essays aims to provide a broader overview of this field, and to explore the use of these with the use of these quantitative technologies in medical and clinical cultures from the seventeenth to the twentieth centuries.
Now in its Fourth Edition, An Introduction to Medical Statistics continues to be a "must-have" textbook for anyone who needs a clear logical guide to the subject. Written in an easy-to-understand style and packed with real life examples, the text clearly explains the statistical principlesused in the medical literature. Taking readers through the common statistical methods seen in published research and guidelines, the text focuses on how to interpret and analyse statistics for clinical practice. Using extracts from real studies, the author illustrates how data can be employed correctly and incorrectly in medicalresearch helping readers to evaluate the statistics they encounter and appropriately implement findings in clinical practice. End of chapter exercises, case studies and multiple choice questions help readers to apply their learning and develop their own interpretative skills. This thoroughly revised edition includes new chapters on meta-analysis, missing data, and survival analysis.
This versatile textbook allows students and teachers to fashion an instructional package that meets diverse learning needs. It provides a wide-ranging look at basic and advanced biostatistical concepts and methods in a format calibrated to individual interests and levels of proficiency. Each topic presentation features introductory comments, real-life examples, a step-by-step outline of the statistical procedure under discussion, an explanation of applications, and numerous practice exercises. Advanced material-which may be included in coursework at the discretion of the instructor-has been noted throughout the text with asterisks, and notes at the end of each chapter extend and enrich the primary material. Early chapters discuss the design of medical studies, descriptive statistics, and introductory ideas of probability theory and statistical inference. Later chapters explore more advanced statistical methods and illustrate important current uses of biostatistics. Statistical methods discussed include * Robustness and nonparametric statistics * Analysis of variance and covariance * Multiple comparisons * Discrimination and classification * Principal component analysis and factor analysis * Survival analysis (including life tables, product-limit estimates, and Cox proportional hazards regression) * Sample sizes for observational studies With more than 390 practice exercises, clear illustrations and graphics, and more than 130 examples, Biostatistics provides a complete detailed seminar, which encourages steady, incremental growth while acting as a catalyst for creative analysis.
This is a new edition of a popular textbook which describes the design and analysis of medical research studies, using many real examples. It includes many questions of readers to test their knowledge.