Science

The Weak Hydrogen Bond

In Structural Chemistry and Biology

Author: Gautam R. Desiraju,Thomas Steiner

Publisher: Oxford University Press on Demand

ISBN: 9780198509707

Category: Science

Page: 507

View: 7568

Review from previous edition 'For crystallographers interested in future advances in the study of hydrogen bonding and their implications for crystal engineering and structural biology, this is a must-read book ' Acta Crystallographica'It is a real pleasure to read the book' Crystallography News'This book is an important monograph for those working on the related structural chemistry of the weak hydrogen bond' MoleculesThe weak or non-conventional hydrogen bond has been the subject of intense scrutiny over recent years. Now available in paperback, this highly acclaimed book provides a critical assessment on this interesting and occasionally controverstial interaction type.
Language Arts & Disciplines

The Weak Hydrogen Bond

In Structural Chemistry and Biology

Author: Gautam R. Desiraju,Thomas Steiner

Publisher: Oxford University Press, USA

ISBN: 9780198502524

Category: Language Arts & Disciplines

Page: 507

View: 7327

The weak or non-conventional hydrogen bond has been the subject of intense scrutiny over recent years. Thought the existence of this type of hydrogen bond was suggested many years ago it was generally relegated to a subsidiary position when compared to the stronger and more well-known forms ofhydrogen bonds. However, a growing body of experimental and theoretical evidence now confirms that hydrogen bonds like C-H...O, O-H..., C-H... and even bonds such as O-H...metal play distinctive roles in structural chemistry and biology. In this book the authors provide a critical assessment on thisinteresting and occasionally controversial interaction type. This book will be of use to all those interested in structural and supramolecular science.
Science

The Nature of the Hydrogen Bond

Outline of a Comprehensive Hydrogen Bond Theory

Author: Gastone Gilli,Paola Gilli

Publisher: OUP Oxford

ISBN: 0191580279

Category: Science

Page: 330

View: 1046

Hydrogen bond (H-bond) effects are known: it makes sea water liquid, joins cellulose microfibrils in trees, shapes DNA into genes and polypeptide chains into wool, hair, muscles or enzymes. Its true nature is less known and we may still wonder why O-H...O bond energies range from less than 1 to more than 30 kcal/mol without apparent reason. This H-bond puzzle is re-examined here from its very beginning and presented as an inclusive compilation of experimental H-bond energies and geometries. New concepts emerge from this analysis: new classes of systematically strong H-bonds (CAHBs and RAHBs: charge- and resonance-assisted H-bonds); full H-bond classification in six classes (the six chemical leitmotifs); and assessment of the covalent nature of strong H-bonds. This leads to three distinct but inter-consistent models able to rationalize the H-bond and predict its strength, based on classical VB theory, matching of donor-acceptor acid-base parameters (PA or pKa), or shape of the H-bond proton-transfer pathway. Applications survey a number of systems where strong H-bonds play an important functional role, namely drug-receptor binding, enzymatic catalysis, ion-transport through cell membranes, crystal design and molecular mechanisms of functional materials.
Fiction

An Introduction to Hydrogen Bonding

Author: George A. Jeffrey

Publisher: Oxford University Press on Demand

ISBN: 9780195095494

Category: Fiction

Page: 303

View: 4875

Hydrogen bonds range from the very strong, comparable with covalent bonds, to the very weak, comparable with van der Waals forces. Most hydrogen bonds are weak attractions with a binding strength about one-tenth of that of a normal covalent bond. Nevertheless, they are very important. Without them, all wooden structures would collapse, cement would crumble, oceans would vaporize, and all living things would disintegrate into inanimate matter. An easy-to-read supplement to the often brief descriptions of hydrogen bonding found in most undergraduate chemistry and molecular biology textbooks, An Introduction to Hydrogen Bonding describes and discusses the current ideas concerning hydrogen bonding, ranging from the very strong to the very weak, with introductions to the experimental and theoretical methods involved. Ideal for courses in chemistry and biochemistry, it will also be useful for structural biology and crystallography courses. For students and researchers interested in supramolecular chemistry, biological structure and recognition, and other sophisticated concepts and methodologies, it provides a careful selection of key references from the vast hydrogen bonding literature.
Science

Hydrogen Bonding - New Insights

Author: Slawomir Grabowski

Publisher: Springer Science & Business Media

ISBN: 140204853X

Category: Science

Page: 524

View: 9184

This book uses examples from experimental studies to illustrate theoretical investigations, allowing greater understanding of hydrogen bonding phenomena. The most important topics in recent studies are covered. This volume is an invaluable resource that will be of particular interest to physical and theoretical chemists, spectroscopists, crystallographers and those involved with chemical physics.
Science

Diffuse X-Ray Scattering and Models of Disorder

Author: Thomas Richard Welberry

Publisher: Oxford University Press on Demand

ISBN: 0198528582

Category: Science

Page: 266

View: 566

Diffuse X-ray scattering is a rich (virtually untapped) source of local structural information over and above that obtained by conventional crystallography. The book aims to show how computer simulation of a model crystal provides a general method by which diffuse scattering of all kinds and from all types of materials can be interpreted and analysed.
Science

The Basics of Crystallography and Diffraction

Author: Christopher Hammond

Publisher: Oxford University Press, USA

ISBN: 9780198505525

Category: Science

Page: 331

View: 5230

A classic textbook providing a clear and comprehensive introduction to the topic of crystallography and diffraction for undregraduate and beginning graduate students and lecturers in physics, chemistry, materials and earth sciences. For this second edition the existing material has been throughly updated.
Science

Chemistry and Biology of Heparin and Heparan Sulfate

Author: Hari G. Garg,Robert J. Linhardt,Charles A. Hales

Publisher: Elsevier

ISBN: 9780080529059

Category: Science

Page: 792

View: 4885

The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area. Comprehensively reviews all aspects of heparin and heparan sulfate research Uniquely describes the chemistry, biology and clinical application of heparins and heparan sulfates in one work Provides an invaluable source of knowledge of current developments for chemists, biochemists, medical doctors, researchers, students and practitioners
Science

Crystallography of Quasicrystals

Concepts, Methods and Structures

Author: Walter Steurer,Sofia Deloudi

Publisher: Springer Science & Business Media

ISBN: 3642018998

Category: Science

Page: 384

View: 369

From tilings to quasicrystal structures and from surfaces to the n-dimensional approach, this book gives a full, self-contained in-depth description of the crystallography of quasicrystals. It aims not only at conveying the concepts and a precise picture of the structures of quasicrystals, but it also enables the interested reader to enter the field of quasicrystal structure analysis. Going beyond metallic quasicrystals, it also describes the new, dynamically growing field of photonic quasicrystals. The readership will be graduate students and researchers in crystallography, solid-state physics, materials science, solid- state chemistry and applied mathematics.
Computers

Handbook of Computational Chemistry

Author: Jerzy Leszczynski

Publisher: Springer Science & Business Media

ISBN: 940070710X

Category: Computers

Page: 1427

View: 6912

This handbook is a guide to current methods of computational chemistry, explaining their limitations and advantages and providing examples of their applications. The first part outlines methods, the balance of volumes present numerous important applications.
Science

Fundamentals of Crystallography

Author: Carmelo Giacovazzo

Publisher: Oxford University Press, USA

ISBN: 9780198509585

Category: Science

Page: 825

View: 3282

Crystallography and structure theory have recently received increasing interest due to their role in understanding biological structures, high-temperature superconductors, and effects on mineral properties related to changes in temperature and pressure. This text offers an account of the wide range of crystallography in various branches of science.The fundamentals, the most frequently used procedures, and experimental techniques are all described, and a number of appendices are devoted to more specialist aspects. The book is an updated edition with emphasis on the range of topical applications. Illustrations should help to clarify the subject matter. To provide a better understanding of the basics of crystallography, a compact disk has been added to this edition, offering the facilities of modern graphics to simulate experiments, show complex images, and provide a number of exercises.
Science

Modern Chromatographic Analysis Of Vitamins

Revised And Expanded

Author: Andre P. De Leenheer,Willy Lambert

Publisher: CRC Press

ISBN: 9780203909621

Category: Science

Page: 632

View: 6940

Third Edition collects and examines the tremendous proliferation of information on chromatographic analysis of fat and water soluble vitamins over the last decade. Extensively describes sample preparation and final measurement.
Science

Implications of Molecular and Materials Structure for New Technologies

Author: Judith A K Howard,Frank H. Allen,Gregory P. Shields

Publisher: Springer Science & Business Media

ISBN: 9401146535

Category: Science

Page: 354

View: 9756

Recent years have seen a dramatic increase in the use of crystal structure information and computational techniques in the design and development of a very wide range of novel materials. These activities now encompass a broad chemical spectrum, reflected in the contributions published here, which cover: modern crystallographic techniques, databases and knowledge bases of experimental results, computational techniques and their interplay with experimental information, hydrogen bonding and other intermolecular interactions, supramolecular assembly and crystal structure prediction, and practical examples of materials design. Each author is a recognised expert and the volume contains state-of-the-art results set in the context of essential background material and augmented by extensive bibliographies. The volume provides a coherent introduction to a rapidly developing field and will be of value to both specialists and non-specialists at the doctoral and post-doctoral levels.
Science

Uniting Electron Crystallography and Powder Diffraction

Author: Ute Kolb,Kenneth Shankland,Louisa Meshi,Anatoly Avilov,William I.F David

Publisher: Springer

ISBN: 9400755805

Category: Science

Page: 434

View: 4702

The polycrystalline and nanocrystalline states play an increasingly important role in exploiting the properties of materials, encompassing applications as diverse as pharmaceuticals, catalysts, solar cells and energy storage. A knowledge of the three-dimensional atomic and molecular structure of materials is essential for understanding and controlling their properties, yet traditional single-crystal X-ray diffraction methods lose their power when only polycrystalline and nanocrystalline samples are available. It is here that powder diffraction and single-crystal electron diffraction techniques take over, substantially extending the range of applicability of the crystallographic principles of structure determination. This volume, a collection of teaching contributions presented at the Crystallographic Course in Erice in 2011, clearly describes the fundamentals and the state-of-the-art of powder diffraction and electron diffraction methods in materials characterisation, encompassing a diverse range of disciplines and materials stretching from archeometry to zeolites. As such, it is a comprehensive and valuable resource for those wishing to gain an understanding of the broad applicability of these two rapidly developing fields.
Science

Intermolecular Forces

An Introduction to Modern Methods and Results

Author: Pierre L. Huyskens,Werner A.P. Luck,Therese Zeegers-Huyskens

Publisher: Springer Science & Business Media

ISBN: 3642762603

Category: Science

Page: 490

View: 4979

The study of intermolecular forces began over one hundred years ago in 1873 with the famous thesis of van der Waals. In recent decades, knowledge of this field has expanded due to intensive research into both its theoretical and the experimental aspects. This is particularly true for the type of very strong cohesive force stressed in 1920 by Latimer and Rodebush: the hydrogen bond, a phenomenon already outlined in 1912 by Moore and Winemill. Hydrogen bonds exert a profound influence on most of the physical and chemical properties of the materials in which they are formed. Not only do they govern viscosity and electrical conductivity, they also intervene in the chemical reaction path which determines the kinetics of chemical processes. The properties of chemical substances depend to a large extent on intermolecular forces. In spite of this fundamental fact, too little attention is given to these properties both in research and in university teaching. For instance, in the field of pharmaceutical research, about 13000 compounds need to be studied in order to find a single new product that can be successfully marketed. The recognition of the need to optimize industrial research efficiency has led to a growing interest in promoting the study of inter molecular forces. Rising salary costs in industry have encou raged an interest in theoretical ideas which will lead to tailor made materials.
Science

Phasing in Crystallography

A Modern Perspective

Author: Carmelo Giacovazzo

Publisher: Oxford University Press

ISBN: 0199686998

Category: Science

Page: 480

View: 2445

The book describes phasing techniques in modern crystallography. The main text is dedicated to their simple description, and further mathematical details are contained in the appendices. Practical aspects are described for each specific method, making it a useful tool for the daily work of practising crystallographers.
Science

Surface Chemistry and Catalysis

Author: Albert F. Carley,Philip Davies,Graham J. Hutchings,Michael S. Spencer

Publisher: Springer Science & Business Media

ISBN: 1475766378

Category: Science

Page: 381

View: 9859

In 2001 Wyn Roberts celebrated both his 70th birthday and 50 years of working in surface science, to use the term "surface science" in its broadest meaning. This book aims to mark the anniversary with a contribution of lasting value, something more than the usual festschrift issue of a relevant journal. The book is divided into three sections: Surface Science, Model Catalysts and Catalysis, topics in which Wyn has always had interests. The authors for each chapter were chosen from some of the many eminent scientists who have worked with Wyn in various ways and are all internationally acknowledged as leaders in their field. The authors have produced authoritative reviews of their own specialties which together result in a book with an unrivalled combination of breadth and depth exploring the most recent developments in surface chemistry and catalysis.
Science

Mass Spectrometry

Principles and Applications

Author: Edmond de Hoffmann,Vincent Stroobant

Publisher: John Wiley & Sons

ISBN: 1118681940

Category: Science

Page: 504

View: 6536

The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications. Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.
Science

Neutron Scattering in Biology

Techniques and Applications

Author: Jörg Fitter,Thomas Gutberlet,John Katsaras

Publisher: Springer Science & Business Media

ISBN: 3540291113

Category: Science

Page: 560

View: 4001

The advent of new neutron facilities and the improvement of existing sources and instruments world wide supply the biological community with many new opportunities in the areas of structural biology and biological physics. The present volume offers a clear description of the various neutron-scattering techniques currently being used to answer biologically relevant questions. Their utility is illustrated through examples by some of the leading researchers in the field of neutron scattering. This volume will be a reference for researchers and a step-by-step guide for young scientists entering the field and the advanced graduate student.
Science

Calcium Orthophosphates

Applications in Nature, Biology, and Medicine

Author: Sergey V. Dorozhkin

Publisher: CRC Press

ISBN: 9814364177

Category: Science

Page: 850

View: 2035

Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophosphates. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. A comprehensive overview of calcium orthophosphates, this book highlights their importance and biomedical uses.