Interventions that delay aging are expected to improve health. In the current US National Institute on Aging's Interventions Testing Program (ITP) the immunosuppressive drug rapamycin was found to increase the maximum life span in mice. These mice started receiving this treatment at an age corresponding to 60 years in humans. Rapamycin targets the same mechanism which was critically involved in the life span extension previously seen in certain mutants of worms flies and mice. The maximum life span was increased in some of these mutants by more than 250 percent, suggesting 1) that the maximum life span is limited by a common mechanism of death, and 2) that humans may possibly gain a few more decades beyond 120 years by interfering in this mechanism. As rapamycin has important adverse effects, this books looks into the underlying mechanisms and describes several natural interventions likely to decrease the rate of aging without using pharmacological drugs.
FACE IT. WE CAN GO ANYTIME. BUT IN SO MANY DIFFERENT WAYS! Death becomes you, and it's just another fact of life explored in Cause of Death, a revealing abundance of startling data, false perceptions, bizarre fallacies, and some totally unexpected statistics about how, why, when, and where we all bite the dust, check out, buy the farm, kick the bucket, and all those other euphemisms for perishing after falling out of bed (roughly 1,800 fitful sleepers a year). It also answers questions most people never even consider (but should): Do crocodiles kill more people than alligators? Are we more prone to commit suicide or murder? How many still die from leprosy? Does salmonella have anything to do with salmon? Can the condition of your toenails predict your mortality? What's the connection between kitty litter and brain damage? Has irony ever killed anyone?* Disease, accidents, occupational hazards, poisons, plagues, infections, murder, fauna and fungi, insect bites, war, and even bison. What's the most popular killer of the decade? The rarest? How many deaths per year by age? Gender? Location? Time of day? Stupidity? All this and more in a book you really shouldn't be living without. * Yes! While experimenting with the safe preservation of food in snow, Sir Francis Bacon caught a cold and died.
When Mrs Sophie Easterberg is found dead on her bedroom floor in the picturesque village of Five Meadows, it is apparent she has been murdered. The obvious suspect is Dave Lucas, an ex-borstal boy recently employed by her, who has since disappeared. Detective-Superintendent Simon Manton of Scotland Yard is despatched to take charge of the case. He soon tracks Lucas down. But is he guilty? And, even if he is, would a jury convict him?
Dr Geoffrey Garrett was for over 30 years a Home Office pathologist. This is his personal memoir, in conjunction with crime journalist Andrew Nott, of many infamous, unusual and heartbreaking cases and a fascinating history of his professional life, giving a unique insight into a pathologist's work. Beginning with a no-holds-barred account of the basic methodology of a post-mortem examination, the book chronicles many memorable cases, including: The discovery of a preserved body on the Yorkshire moors later identified as the first victim of the Moors Murderers The murders of three policemen plus the apprehension of a murderer who turned out to be a policeman's son An examination of sex crimes The Moss: a seminal piece on Manchester's 'Bronx' - Dr Garrett reveals life in the ghetto, the drug gangs and how they operate How a man's face, burned beyond recognition, was reconstructed to help solve a murder Plus examples of many other baffling crimes which were resolved on the pathologist's table.