Science

Electroanalytical Methods Of Biological Materials

Author: Anna Brajter-toth

Publisher: CRC Press

ISBN:

Category: Science

Page: 552

View: 147

This text details contemporary electroanalytical strategies of biomolecules and electrical phenomena in biological systems. It presents significant developments in sequence-specific DNA detection for more efficient and cost-effective medical diagnosis of genetic and infectious diseases and microbial and viral pathogens. The authors discuss the late
Science

Electroanalytical Methods Of Biological Materials

Author: Anna Brajter-toth

Publisher: CRC Press

ISBN:

Category: Science

Page: 552

View: 668

This text details contemporary electroanalytical strategies of biomolecules and electrical phenomena in biological systems. It presents significant developments in sequence-specific DNA detection for more efficient and cost-effective medical diagnosis of genetic and infectious diseases and microbial and viral pathogens. The authors discuss the late
Science

Electroanalytical Methods Of Biological Materials

Author: Anna Brajter-toth

Publisher: CRC Press

ISBN:

Category: Science

Page: 552

View: 749

This text details contemporary electroanalytical strategies of biomolecules and electrical phenomena in biological systems. It presents developments in sequence-specific DNA detection for more efficient medical diagnosis of genetic and infectious diseases and microbial and viral pathogens.
Science

Electrochemical Biosensors

Author: Ali A. Ensafi

Publisher: Elsevier

ISBN:

Category: Science

Page: 388

View: 712

Electrochemical Biosensors summarizes fundamentals and trends in electrochemical biosensing. It introduces readers to the principles of transducing biological information to measurable electrical signals to identify and quantify organic and inorganic substances in samples. The complexity of devices related to biological matrices makes this challenging, but this measurement and analysis are critically valuable in biotechnology and medicine. Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial and agricultural applications. Describes several electrochemical methods used as detection techniques with biosensors Discusses different modifiers, including nanomaterials, for preparing suitable pathways for immobilizing biomaterials at the sensor Explains various types of signal monitoring, along with several recognition systems, including antibodies/antigens, DNA-based biosensors, aptamers (protein-based), and more
Science

Chemical Sensors and Biosensors

Author: Florinel-Gabriel Banica

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 576

View: 369

Key features include: Self-assessment questions and exercises Chapters start with essential principles, then go on to addressmore advanced topics More than 1300 references to direct the reader to keyliterature and further reading Highly illustrated with 450 figures, including chemicalstructures and reactions, functioning principles, constructivedetails and response characteristics Chemical sensors are self-contained analytical devices thatprovide real-time information on chemical composition. A chemicalsensor integrates two distinct functions: recognition andtransduction. Such devices are widely used for a variety ofapplications, including clinical analysis, environment monitoringand monitoring of industrial processes. This text provides anup-to-date survey of chemical sensor science and technology, with agood balance between classical aspects and contemporary trends.Topics covered include: Structure and properties of recognition materials and reagents,including synthetic, biological and biomimetic materials,microorganisms and whole-cells Physicochemical basis of various transduction methods(electrical, thermal, electrochemical, optical, mechanical andacoustic wave-based) Auxiliary materials used e.g. synthetic and natural polymers,inorganic materials, semiconductors, carbon and metallicmaterials properties and applications of advanced materials (particularlynanomaterials) in the production of chemical sensors andbiosensors Advanced manufacturing methods Sensors obtained by combining particular transduction andrecognition methods Mathematical modeling of chemical sensor processes Suitable as a textbook for graduate and final year undergraduatestudents, and also for researchers in chemistry, biology, physics,physiology, pharmacology and electronic engineering, this bookisvaluable to anyone interested in the field of chemical sensors andbiosensors.
Science

Signal-Switchable Electrochemical Systems

Author: Evgeny Katz

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 320

View: 511

A guide to the biological control over electronic systems that lead the way to wearable electronics and improved drug delivery In recent years, this area of electrochemical systems has developed rapidly and achieved significant progress. Signal-Switchable Electrochemical Systems offers an overview to the wide-variety of switchable electrochemical systems and modified electrodes. The author?a noted researcher and expert on the topic?summarizes research efforts of many groups in a range of universities and countries. The book explores various types of external signals that are able to modify electrode interfaces, for example electrical potential, magnetic field, light, as well as chemical and biochemical inputs. Multifunctional properties of the modified interfaces allow their responses to complex combinations of external signals. These are integrated with unconventional biomolecular computing systems logically processing multiple biochemical signals. This approach allows the biological control over electronic systems. The text explores the applications in different areas, including unconventional computing, biofuel cells and signal-triggered molecular release in electrochemical systems. This important guide: -Provides an overview to the biological control over electronic systems and examines the key applications in biomedicine, electrochemical energy conversion and signal-processing -Offers an important text written by a highly cited researcher and pioneer in the field -Contains a summary of research efforts of an international panel of scholars representing various universities and countries -Presents a groundbreaking book that provides an introduction to this interdisciplinary field Written for scientists working with electrochemical systems and applications with signal-responsive materials, Signal-Switchable Electrochemical Systems presents an overview of the multidisciplinary field of adaptable signal-controlled electrochemical systems and processes and highlights their key aspects and future perspectives.
Science

Electrochemistry for Bioanalysis

Author: Bhavik A. Patel

Publisher: Elsevier

ISBN:

Category: Science

Page: 330

View: 849

Electrochemistry for Bioanalysis provides a comprehensive understanding of the benefits and challenges of the application of electrochemical and electroanalytical techniques for measurement in biological samples. The book presents detailed information on measurement in a host of various biological samples from single cells, tissues and in vivo. Sections cover real insights surrounding key experimental design and measurement within multiple complex biological environments. Finally, users will find discussions on emerging topics such as electrogenerated chemiluminescence and the use of additive manufacturing for biosensor fabrication. Continuous learning reinforcement throughout the book, including problems for self-assessment, make this an ideal resource. Balances the fundamentals of electrochemical and neurochemical methods with current advances in the field of bioanalysis Includes self-assessment scenarios on experimental design and validation to teach readers key factors and considerations in measurement Highlights applications (such as sensors and biosensors) and key points within each chapter
Technology & Engineering

Electroanalytical Applications of Quantum Dot-Based Biosensors

Author: Bengi Uslu

Publisher: Elsevier

ISBN:

Category: Technology & Engineering

Page: 476

View: 734

Quantum dots (QDs) are hybrid organic/inorganic nanoparticles with novel physical properties. QDs have two components: an inorganic core and an optically active coated shell. Moreover, surface coatings can be applied to QDs to modify the particle as needed for experiments. Hydrophilic coatings prevent leaking of metal cargo from the core, enhancing the solubility in biological contexts and bind molecules, such as receptor–ligands, antibodies, therapeutic, and diagnostic macromolecules for enhanced effects. Their high surface-to-volume ratio allows multiple functional groups to attach onto the surface of the particles at constant surface volume. Silicon-, gallium-, indium-, or germanium-based; cadmium-based; and carbon-based QDs have already been used in many applications, such as imaging probes for the engineering of multifunctional nanodevices. Superior properties of QDs make them an excellent system in technology and biotechnology. This book describes electroanalytical applications of QD-based nanobiosensors, including brief information about the synthesis and characterization of QDs and basics of electroanalytical methods, followed by QDs in electrochemical biomimetic sensors, QDs in microchips, inorganic materials doped QDs, QD-based electrochemical DNA biosensors, electroluminescence for biomarker analysis using aptamer-based QDs, QD-based photoelectrochemical techniques, enzyme-based nanobiosensors using QDs, QD-based electrochemical immunosensors, and QD-modified nanosensors in drug analysis. Outlines QD-based applications for drug, food, clinical, and environmental science Shows how the properties of QDs make them effective ingredients in biosensing applications Assesses the major challenges in integrating QDs in biosensing systems
Technology & Engineering

Biosensors: an Introduction

Author:

Publisher: Vieweg+Teubner Verlag

ISBN:

Category: Technology & Engineering

Page: 212

View: 929

The need and the idea for this book came out of the author's involvement in delivering a lecture course on biosensors to final year students of the highly successful Honours Degree in Applied Biochemical Sciences at the University of Ulster at lordanstown. This four-year course was designed to meet the needs of local industry in Northern Ireland. It includes courses in chemistry, biochemistry, analytical methods, industrial studies and computing, business studies, projects in science and business studies, with the third year spent on placement in industry, usually in the UK or Ireland. The 12 lecture + 12 hour laboratory course in biosensors is part of a module called 'special topics', which also includes bioinorganic chemistry and chemotherapeutics. There were not many books covering biosensors, and those that did exist were mostly specialised, but good reference books for further reading. A reasonable background knowledge of electro analytical methods is needed as a prerequisite for a study of biosensors. In our course this material is covered as part of the advanced analytical methods module. A substantial part of this book is devoted to electrochemical transducers. The book commences with an introductory chapter about the nature of biosensors, their components and applications. This is followed by a chapter surveying the groups of biological components involved in biosensors. Chapter 3 covers the various ways in which the biological components can be attached to the transducers, i.e. immobilised.
Science

Electroanalytical Stripping Methods

Author: Kh. Brainina

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 198

View: 948

A monograph on the theory of this procedure and its application to environmental monitoring. Considers all variants of stripping methods as a group of techniques used to study and analyze both solutions and solids. Reflects new qualitative standards attained by recently used electroanalytical stripping methods.
Science

Ultrathin Electrochemical Chemo- and Biosensors

Author: Vladimir M. Mirsky

Publisher: Springer Science & Business Media

ISBN:

Category: Science

Page: 358

View: 672

Traditional biological sensors, based on enzymatic receptors and potentiometric or amperometric transducers are well reviewed and are nowadays even included extensively in many textbooks. The editors of this volume, the 2nd in the new Springer Series on Chemical and Biosensors, have focussed exclusively on alternative types of chemical and biological sensors or sensor-like structures. Special attention is given to sensor principles based on the use of linear or non-linear impedance spectroscopy. After self-assembled monolayers have become a viable technology for the immobilization of organic molecules on electrodes and for the formation of covalently stabilized receptor layers and even more sophisticated organic nano- and microstructures, this has led to the development of numerous analytical applications of impedometric sensor methods. These new and very promising types of sensors, their technology and performance in real world applications form the main topic of this book written by leading experts from around the world.
Technology & Engineering

Comprehensive Biomaterials

Author: Paul Ducheyne

Publisher: Elsevier

ISBN:

Category: Technology & Engineering

Page: 3672

View: 271

Comprehensive Biomaterials brings together the myriad facets of biomaterials into one, major series of six edited volumes that would cover the field of biomaterials in a major, extensive fashion: • Volume 1: Metallic, Ceramic and Polymeric Biomaterials • Volume 2: Biologically Inspired and Biomolecular Materials • Volume 3: Methods of Analysis • Volume 4: Biocompatibility, Surface Engineering, and Delivery Of Drugs, Genes and Other Molecules • Volume 5: Tissue and Organ Engineering • Volume 6: Biomaterials and Clinical Use Experts from around the world in hundreds of related biomaterials areas have contributed to this publication, resulting in a continuum of rich information appropriate for many audiences. The work addresses the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, and strategic insights for those entering and operational in diverse biomaterials applications, research and development, regulatory management, and commercial aspects. From the outset, the goal was to review materials in the context of medical devices and tissue properties, biocompatibility and surface analysis, tissue engineering and controlled release. It was also the intent both, to focus on material properties from the perspectives of therapeutic and diagnostic use, and to address questions relevant to state-of-the-art research endeavors. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance as well as future prospects Presents appropriate analytical methods and testing procedures in addition to potential device applications Provides strategic insights for those working on diverse application areas such as R&D, regulatory management, and commercial development
Science

Electroanalytical Techniques in Clinical Chemistry and Laboratory Medicine

Author: Joseph Wang

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 188

View: 281

This practical introduction to all the elextroanalytical techniques that are used in clinical chemistry and laboratory medicine is the only in-depth treatment of the subject available. The author presents the relevant theory and uses numerous examples to illustrate the scope and possibilities of electroanalysis in the clinical laboratory. The material covered includes the principles and bioanalytical applications of voltammetry and potentiometry, electrochemical biosensors, detectors to flowing steams, and in vivo electrochemistry. The book should be useful to those considering the use of electroanalysis in their laboratories and to clinical chemists experienced in electroanalysis

Recent Advances in Analytical Electrochemistry 2007

Author: Kenneth I. Ozoemena

Publisher:

ISBN:

Category:

Page: 307

View: 959

Electrochemical sensors occupy an enviable position amongst the analytical probes available for applied analytical chemistry, e.g. in process control and in the analysis of clinical, industrial and environmental samples. When compared to other analytical techniques (such as spectroscopy, mass spectrometry and chromatography) electrochemical techniques have continually proved to be more sensitive and selective towards redox-active organic and inorganic analytes, faster response times, more easily to be miniaturized (portability) for field or on-the-spot-analysis, and yet less expensive. The past 15 years have witnessed an unprecedented number of publications in electroanalysis because of the ever-increasing discovery and/or synthesis of many new electroactive materials suitable for the design and fabrication of high-performance electrochemical sensors. This book is an attempt to provide some recent research topics in analytical electrochemistry notably, carbon naotube-based electrodes, diamond-based electrodes, metallophthalocyanine-based electrodes, field-effect potentiometric biosensors, impedance spectroscopy, voltammetry in coupled electrochemical techniques for trace metal analysis, microelectrochemistry for biomedical analysis, screen-printed electrodes, polyaniline polymers in peroxide-based amperometric sensors. Purposefully, authors invited for this book come from different countries across the globe and represent a broad range of researchers in electroanalytical materials and methods. It is difficult (if not impossible) to cover the vast areas of electroanalytical chemistry being constantly developed, however, the authors have, in remarkable different manners, addressed the main questions that bind this volume together: What constitute the design and fabrication strategies being explored and employed? What chemical and biological materials are being explored as potential and viable electrode materials in order to improve electrochemical response, i.e., linear concentration range, sensitivity, selectivity, detection limits, simplicity/portability, durability/stability and response time? The first chapter of the book introduces electrochemical sensors, and gives the methods generally used in electrode modification as well as the mechanistic pathways for the electroanalytical detection of analytes. Although the chapter specifically focused on metallophthalocyanine-based electrodes, the principle certainly applies to most known modified electrodes. In chapter 2, Hanrahan and Zhou, provide an overview of recent voltammetric and select coupled electrochemical techniques for trace metal analysis. In this chapter, these authors gave some theoretical backgrounds concerning the various techniques and discussed the specific applications from direct laboratory and field-based studies. Carbon nanotube-based electrodes are gaining intense research interests among electroanalysts world-wide. The groups of Compton and Banks, to my knowledge, have published more works in this area than any other workers in this field. In Chapter 3, these groups review the recent investigations of carbon nanotube modified electrodes in electroanalysis, as well as reporting on fundamental advances in understanding the electrochemical reactivity of carbon nanotubes. In Chapters 4 and 5, Iwuoha and co-workers describe the works on nanostructuring of conducting polymers, focussing mainly on polypyrroles, polythiophenes and polyanilines, for electrochemical sensing. Boron-doped electrodes represent one of the most promising electrode materials in electroanalysis, yet rarely reported in the literature. In chapter 6, Chailapakul and co-workers highlight some important previous and more recent works in this area. Chapters 7 to 9 deal mainly with biomedical analysis. In chapter 7, Estrela and co-workers reviewed some of the interesting designs and applications of various field-effect potentiometric devices for bioanalysis. The authors contend that the application of thin film transistors technology to biosensors is highly promising since such technology is inherently low cost and yet capable of providing integrated circuits of a complexity comparable to conventional microchips. In chapter 8, Bala and co-workers reviewed some advances on screen-printing technology and the application of screen-printed electrodes for clinical and environmental analysis. Grazl, in Chapter 9, describes the recent advances in his group on the application of microelectrochemistry in biomedical analysis. The book is concluded (Chapter 10) by an original work by Baker and co-workers on the use of electrochemical impedance spectroscopy for the characterization and investigation of transition metal doped tin oxide thin film materials as potential catalysts for anodic oxidation of certain analytes, notably hydroquinones and phenols, in aqueous environment. I have no doubt that this book will be of valuable interests to electrochemists, analytical chemists, applied material scientists and scientific researchers in the environmental, biomedical and industrial fields. Research students in elelctroanalytical chemistry and their supervisors alike will find the book interesting, timely, and informative with over a thousand referenced recent articles. I would like to thank the authors who, despite their extreme busy schedule of teaching and research (and even administration), found time to make this book a reality. The advisory role played by Prof Emmanuel I. Iwuoha during the course of this work is greatly appreciated.
Science

Bioelectrochemistry

Author: Philip N. Bartlett

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 494

View: 396

Bioelectrochemistry: Fundamentals, Experimental Techniques and Application, covers the fundamental aspects of the chemistry, physics and biology which underlie this subject area. It describes some of the different experimental techniques that can be used to study bioelectrochemical problems and it describes various applications of biolelectrochemisty including amperometric biosensors, immunoassays, electrochemistry of DNA, biofuel cells, whole cell biosensors, in vivo applications and bioelectrosynthesis. By bringing together these different aspects, this work provides a unique source of information in this area, approaching the subject from a cross-disciplinary viewpoint.
Science

Analytical Electrochemistry

Author: Joseph Wang

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 272

View: 303

Third Edition covers the latest advances in methodologies, sensors,detectors, and mIcrochips The greatly expanded Third Edition of this internationallyrespected text continues to provide readers with a completepanorama of electroanalytical techniques and devices, offering abalancebetween voltammetric and potentiometric techniques.Emphasizing electroanalysis rather than physical electrochemistry,readers gain a deep understanding of the fundamentals ofelectrodereactions and electrochemical methods. Moreover, readerslearn to apply their newfoundknowledge and skills to solvereal-world analytical problems. The text consists of six expertly crafted chapters: * Chapter 1 introduces fundamental aspects of electrode reactionsand the structure of the interfacial region * Chapter 2 studies electrode reactions and high-resolution surfacecharacterization, using techniques ranging from cyclic voltammetryto scanning probe microscopies * Chapter 3 features an overview of modern finite-currentcontrolled potential techniques * Chapter 4 presents electrochemical instrumentation and electrodematerials, including modified electrodes andultramicroelectrodes * Chapter 5 details the principles of potentiometric measurementsand various classes of ion selective electrodes * Chapter 6 explores the growing field of chemical sensors,including biosensors, gas sensors, microchip devices, and sensorarrays Among the new topics covered, readers discover DNA biosensors,impedance spectroscopy, detection of capillary electrophoresis,diamond electrodes, carbon-nanotube and nanoparticle-based arraysand devices, large-amplitude AC voltammetry, solid-stateion-selective electrodes, ion selective electrodes for traceanalysis, and lab-on-a-chip devices. New figures, worked examples,and end-of-chapter questions have also been added to thisedition. Given the rapid pace of discovery and growth of new applications inthe field, this text is essential for an up-to-date presentation ofthe latest advances in methodologies, sensors, detectors, andmicrochips. It is recommended for graduate-level courses inelectroanalytical chemistry and as a supplement for upper-levelundergraduate courses in instrumental analysis. The text also meetsthe reference needs for any industry, government, or academiclaboratory engaged in electroanalysis and biosensors.
Science

Nanobioelectrochemistry

Author: Frank N. Crespilho

Publisher: Springer Science & Business Media

ISBN:

Category: Science

Page: 138

View: 487

Nanobioelectrochemistry covers the modern aspects of bioelectrochemistry, nanoscience and materials science. The combination of nanostructured materials and biological molecules enables the development of biodevices capable to detect specific substances. Furthermore, by using the bioelectrochemistry approach, the interaction between bio-systems and nanostructured materials can be studied at the molecular level, where several mechanisms of molecular behavior are elucidate from redox reactions. The combination of biological molecules and novel nanomaterials components is of great importance in the process of developing new nanoscale devices for future biological, medical and electronic applications. This book describes some of the different electrochemical techniques that can be used to study new strategies for patterning electrode surfaces with enzymes, organelles, cells and biomimetic systems. Also, it focuses on how enzymes and microorganisms can be used as biological catalysts in fuel cells for green power generation. By bringing together these different aspects of nanobioelectrochemistry, this book provides a valuable source of information for many students and scientists.