Science

Indoles, Part 4

Author: J. Edwin Saxton

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 995

View: 644

Internationally renowned specialists present a comprehensive survey of the latest advances in this area. The biosynthetic and structural relationships of these compounds are summarized and newly discovered alkaloids described. Discusses versatile biomimetic procedures as well as the pharmacology and clinical applications of monoterpenoid indole alkaloids. Botanical names of all plants cited have been extensively referenced.
Science

Monoterpenoid Indole Alkaloids, Supplement to Part 4

Author: J. Edwin Saxton

Publisher: Wiley

ISBN:

Category: Science

Page: 860

View: 965

Internationally renowned specialists present a comprehensive survey of the latest advances in this area. The biosynthetic and structural relationships of these compounds are summarized and newly discovered alkaloids described. Discusses versatile biomimetic procedures as well as the pharmacology and clinical applications of monoterpenoid indole alkaloids. Botanical names of all plants cited have been extensively referenced.
Science

Isoxazoles

Author: Paola Grünanger

Publisher: Wiley-Interscience

ISBN:

Category: Science

Page: 904

View: 155

This new volume in a highly regarded, established series provides complete coverage of the heterocyclic chemistry of isoxazoles.
Science

Indoles

Author: William J. Houlihan

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 616

View: 132

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.
Science

Chromans and Tocopherols

Author: Gwynn P. Ellis

Publisher: Wiley-Interscience

ISBN:

Category: Science

Page: 469

View: 245

Professionals in the field comprehensively summarize all the literature that pertains to known members of these classes of compounds. An extensive subject index and comprehensive tables of all recognized compounds permit easy location of data.
Science

Indoles

Author: William J. Houlihan

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 587

View: 113

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.
Medical

Monoterpenoid Indole Alkaloids

Author: John Edwin Saxton

Publisher: Wiley-Blackwell

ISBN:

Category: Medical

Page: 848

View: 995

Internationally renowned specialists present a comprehensive survey of the latest advances in this area. The biosynthetic and structural relationships of these compounds are summarized and newly discovered alkaloids described. Discusses versatile biomimetic procedures as well as the pharmacology and clinical applications of monoterpenoid indole alkaloids. Botanical names of all plants cited have been extensively referenced.
Science

Indoles

Author: William J. Houlihan

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 586

View: 850

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.
Science

Indoles, Part 4

Author: J. Edwin Saxton

Publisher: Wiley-Interscience

ISBN:

Category: Science

Page: 995

View: 683

Internationally renowned specialists present a comprehensive survey of the latest advances in this area. The biosynthetic and structural relationships of these compounds are summarized and newly discovered alkaloids described. Discusses versatile biomimetic procedures as well as the pharmacology and clinical applications of monoterpenoid indole alkaloids. Botanical names of all plants cited have been extensively referenced.
Heterocyclic compounds

Heterocycles

Author:

Publisher:

ISBN:

Category: Heterocyclic compounds

Page:

View: 820

Science

Advances in Cycloaddition

Author: Michael Harmata

Publisher: Elsevier

ISBN:

Category: Science

Page: 248

View: 353

This volume presents work from six different groups working on various aspects of cycloaddition chemistry. José Mascareñas gives us a very interesting account of the chemistry of &Bgr;-alkoxy-&ggr;-pyrones and related species. Al Padwa and Chris Staub discuss further advances in rhodium carbenoid chemistry and the unusual cycloaddition processes possible with these intermediates. Higher order cycloadditions mediated by transition metals highlight Jim Rigby's update on his group's efforts in this area. Lily Lee and John Snyder present us with a detailed account of the indole ring as a dienophile, challenging us to consider the untapped potential in this area. Brian Keay and Ian Hunt discuss the intramolecular Diels-Alder reactions of furan; a report that is both top-notch science, and what could be a great learning tool for students who need to see how fundamental chemical principles can and should be applied to synthetic problems. Finally, Kay Brummond introduces us to a new version of the Pauson-Khand reactions, one that will no doubt be further exploited in productive ways by her group well into the future.
Science

Indoles, Part 4

Author: J. Edwin Saxton

Publisher: Wiley-Interscience

ISBN:

Category: Science

Page: 995

View: 653

Internationally renowned specialists present a comprehensive survey of the latest advances in this area. The biosynthetic and structural relationships of these compounds are summarized and newly discovered alkaloids described. Discusses versatile biomimetic procedures as well as the pharmacology and clinical applications of monoterpenoid indole alkaloids. Botanical names of all plants cited have been extensively referenced.
Science

Catalytic Cascade Reactions

Author: Peng-Fei Xu

Publisher: John Wiley & Sons

ISBN:

Category: Science

Page: 440

View: 634

Demonstrates the advantages of catalytic cascade reactions for synthesizing natural products and pharmaceuticals Riding the wave of green chemistry, catalytic cascade reactions have become one of the most active research areas in organic synthesis. During a cascade reaction, just one reaction solvent, one workup procedure, and one purification step are needed, thus significantly increasing synthetic efficiency. Featuring contributions from an international team of pioneers in the field, Catalytic Cascade Reactions demonstrates the versatility and application of these reactions for synthesizing valuable compounds. The book examines both organocatalysis and transition-metal catalysis reactions, bringing readers up to date with the latest discoveries and activities in all major areas of catalytic cascade reaction research. Catalytic Cascade Reactions begins with three chapters dedicated to organocatalytic cascade reactions, exploring amines, Brønsted acids, and the application of organocatalytic cascade reactions in natural product synthesis and drug discovery. Next, the book covers: Gold-catalyzed cascade reactions Cascade reactions catalyzed by ruthenium, iron, iridium, rhodium, and copper Palladium-catalyzed cascade reactions of alkenes, alkynes, and allenes Application of transition-metal catalyzed cascade reactions in natural product synthesis and drug discovery Engineering mono- and multifunctional nanocatalysts for cascade reactions Multiple-catalyst-promoted cascade reactions All chapters are thoroughly referenced, providing quick access to important original research findings and reviews so that readers can explore individual topics in greater depth. Drawing together and analyzing published findings scattered across the literature, this book provides a single source that encapsulates our current understanding of catalytic cascade processes. Moreover, it sets the stage for the development of new catalytic cascade reactions and their applications.
Science

The Alkaloids

Author:

Publisher: Academic Press

ISBN:

Category: Science

Page: 259

View: 413

The Alkaloids, Volume 81, the newest release in a series that has covered the topic for more than 60 years, covers all aspects of alkaloids, including their chemistry, biology and pharmacology. Sections in this new release cover Bisbenzylisoquinoline Alkaloids, Alkaloids of the Lauraceae, and The Chemical Synthesis and Applications of Tropane Alkaloids, amongst other topics. Provides the latest information on the study of alkaloids Covers their chemistry, biology, pharmacology and medical applications Contains more than 70 published volumes in this interesting field of study
Medical

Toxic Plants of North America

Author: George E. Burrows

Publisher: John Wiley & Sons

ISBN:

Category: Medical

Page: 1390

View: 945

Toxic Plants of North America, Second Edition is anup-to-date, comprehensive reference for both wild and cultivatedtoxic plants on the North American continent. In addition tocompiling and presenting information about the toxicology andclassification of these plants published in the years since theappearance of the first edition, this edition significantly expandscoverage of human and wildlife—both free-roaming andcaptive—intoxications and the roles of secondary compoundsand fungal endophytes in plant intoxications. More than 2,700 new literature citations document identificationof previously unknown toxicants, mechanisms of intoxication,additional reports of intoxication problems, and significantchanges in the classification of plant families and genera andassociated changes in plant nomenclature. Toxic Plants of NorthAmerica, Second Edition is a comprehensive, essential resourcefor veterinarians, toxicologists, agricultural extension agents,animal scientists, and poison control professionals. Key features Presents comprehensive, detailed toxicologic information onwild and cultivated toxic plants found in North America Offers information on both animal and human intoxications Brings together information on plant morphology anddistribution, associated disease problems, disease genesis,clinical signs, pathologic changes, and treatment approaches Provides information on additional toxic species andexplanations of taxonomic revisions in plant classification andnomenclature Incorporates additional information relevant to small andexotic animal practices Includes more than 1,000 images illustrating plant features anddistributions, principal toxicants, and pathways of intoxication; aglossary of toxicological, botanical, and chemical terms; and acomprehensive index
Medical

Analogue-based Drug Discovery II

Author: János Fischer

Publisher: John Wiley & Sons

ISBN:

Category: Medical

Page: 564

View: 926

Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case studies. Like its precursor, this volume also contains a general section discussing universally applicable strategies for analog discovery and development. Spanning a wide range of therapeutic fields and chemical classes, the two volumes together constitute the first systematic approach to drug analog development. Of interest to virtually every researcher working in drug discovery and pharmaceutical chemistry.
Science

Alkaloids: Chemical and Biological Perspectives

Author: S. William Pelletier

Publisher: Springer Science & Business Media

ISBN:

Category: Science

Page: 365

View: 697

Volume 8 of this series presents four timely reviews on alkaloids: Chapter 1 is a magnificent and monumental review of curare, "a group of dart and/or arrow poisons varying in composition and featuring muscle relaxation as their basic pharmacological action." The fascinating history of curare is recounted, beginning with early encounters by the Spanish Conquistadores through its use as arrow poisons by the forest tribes in hunting and warfare, its chemistry, ethnography, botany and pharmacology. A terminal section of this chapter treats the development of modern muscle relaxants. This chapter thus traces how curare-initially only a crude plant extract-has given rise to the widely used and very important neuromuscular blocking agents of today. The precise role of plant secondary metabolites and their interactions with insect herbivores have been focal points for research by chemists, botanists and entomologists for many years. Alkaloids and their glycosides are frequently involved as feeding deterrents. Chapter 2 treats the relationships between the chemistry of alkaloids in host plants and the effects that these compounds may have on insect herbivores. Interestingly, an alkaloid produced by a plant may manifest different effects on different insects.
Science

Modern Phosphonate Chemistry

Author: Philippe Savignac

Publisher: CRC Press

ISBN:

Category: Science

Page: 552

View: 659

A century after their discovery, phosphonates have become important compounds recognized both for their use as efficient reagents in organic synthesis and for their biological and industrial importance. This unique, up-to-date reference presents a concise summary of the state of the art in phosphonate chemistry, covering the role of phosphonates in