Compiled with the most sophisticated chromatographic and spectrometric instruments available, this complete and self-contained seven-volume reference provides forensic, toxicology, and clinical laboratories with up-to-date information on 1,600 drugs and drug-related compounds-one of the largest collections of analytical data generated from a single source. Instrumental Data for Drug Analysis contains timely, quality data presented in a large, easily usable format. It is an essential reference in the libraries of all toxicology, analytical chemistry, and forensic specialists and laboratories.
With the critical role of statistics in the design, conduct, analysis and reporting of clinical trials or observational studies intended for regulatory purposes, numerous guidelines have been issued by regulatory authorities around the world focusing on statistical issues related to drug development. However, the available literature on this important topic is sporadic, and often not readily accessible to drug developers or regulatory personnel. This book provides a systematic exposition of the interplay between the two disciplines, including emerging themes pertaining to the acceleration of the development of pharmaceutical medicines to serve patients with unmet needs. Features: Regulatory and statistical interactions throughout the drug development continuum The critical role of the statistician in relation to the changing regulatory and healthcare landscapes Statistical issues that commonly arise in the course of drug development and regulatory interactions Trending topics in drug development, with emphasis on current regulatory thinking and the associated challenges and opportunities The book is designed to be accessible to readers with an intermediate knowledge of statistics, and can be a useful resource to statisticians, medical researchers, and regulatory personnel in drug development, as well as graduate students in the health sciences. The authors’ decades of experience in the pharmaceutical industry and academia, and extensive regulatory experience, comes through in the many examples throughout the book.
With ever-rising healthcare costs, evidence generation through Health Economics and Outcomes Research (HEOR) plays an increasingly important role in decision-making about the allocation of resources. Accordingly, it is now customary for health technology assessment and reimbursement agencies to request for HEOR evidence, in addition to data from clinical trials, to inform decisions about patient access to new treatment options. While there is a great deal of literature on HEOR, there is a need for a volume that presents a coherent and unified review of the major issues that arise in application, especially from a statistical perspective. Statistical Topics in Health Economics and Outcomes Research fulfils that need by presenting an overview of the key analytical issues and best practice. Special attention is paid to key assumptions and other salient features of statistical methods customarily used in the area, and appropriate and relatively comprehensive references are made to emerging trends. The content of the book is purposefully designed to be accessible to readers with basic quantitative backgrounds, while providing an in-depth coverage of relatively complex statistical issues. The book will make a very useful reference for researchers in the pharmaceutical industry, academia, and research institutions involved with HEOR studies. The targeted readers may include statisticians, data scientists, epidemiologists, outcomes researchers, health economists, and healthcare policy and decision-makers.
United States by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Transportation and Treasury, and Independent Agencies Appropriations
PRINCIPLES OF INSTRUMENTAL ANALYSIS places an emphasis on the theoretical basis of each type of instrument, its optimal area of application, its sensitivity, its precision, and its limitations.You'll also learn about elementary analog and digital electronics, computers, and treatment of analytical datA. Visit the book companion website for tutorials on instrumental methods, Excel files of data analysis and simulations of analytical techniques to help you visualize important concepts in this course, and selected papers from the chemical literature to stimulate interest and provide background information for study.
With this handbook, these users can find information about the most common analytical chemical techniques in an understandable form, simplifying decisions about which analytical techniques can provide the information they are seeking on chemical composition and structure.
Federal aid to medical care research by National Institutes of Health (U.S.). Division of Public Information
Domestic Violence is not just a public health and criminal justice problem, it is also an issue of universal human rights that needs immediate and vigorous attention. How we measure the prevalence of Domestic Violence, what we identify as the risk factors, which theories seem to provide most help in understanding and responding to Domestic Violence, which preventive and treatment programs seem most effective and the respective roles of the health and criminal justice systems, are all questions of vital importance in society's response to the problem.